VS Enterprise 2015 (Update 2) - Refactor/Navigate menus disabled and shortcuts unavailable

After updating VS 2015 to Update 2, ReSharper refactors cease to function. The "Refactor" and "Navigate" menus are disabled in both the top menu and context menus. All shortcuts result in the error - "The key combination (...) is bound to command (Resharper_...) which is not currently available"

I've seen suggestions that my cursor focus is on the wrong object or that the key shortcuts need to be remapped. This isn't the case - the ability to refactor is disabled on any solution and in any scenario.

I attempted clearing out %LocalAppData%\JetBrains\Transient\ReSharperPlatformVs14\v05 per the suggestion on post Refactor Menu disabled (VS2015)

This worked, but only very briefly. I was able to use the Refactor menu while the solution was still loading, however, once everything initialized, including ReSharper, the menus are grayed out again. 

Here's what I've tried:

• Restarted VS / Windows
• Updated Visual Studio
• Updated Resharper
• Repaired Resharper
• Reset all settings (via Import and Export Settings Wizard)
• Deleted everything in %LocalAppData%\JetBrains\Transient\ReSharperPlatformVs14\v05
• Turned off and on solution-wide analysis
• Cleared R# solution cache

this is what the solution context menu looks like:

from the text editor - right-click on a class declaration:

here's one of the general shortcut errors:

Lots of errors detected, though the solution builds fine. I can't navigate this link:

My VS 2015 info: