I have VS2005 installed with ReSharper2.0 build219 installed (no other plugins). Great! It works fine, until I lock my machine when I leave it. When I've logged back, Visual Studio is totally locked - completely non-responsive in everyway, and it stays like that - can't even quit! The only way to get it back is to close it down in the task manager and re-start the software.
Guess this will eventually get fixed.