I'm using 4.5.2 since a few days, after having switched back from 4.5.1 to 4.5.0 because 4.5.1 was much slower. I'm disappointed that 4.5.2 still has the same problem:
After VS starts, the C# editor is very fast. But after working for like 1-2 hours, the editor becomes very slow, pausing for 0.5-1 sec pause after around every 5th key stroke. This gives some kind of "shaky" feeling when entering text. After I go to Tools => Add-In Manager, disable and re-enable R# there, the behaviour is back to normal, at least for the next hour. So it is clearly a R# problem, WHICH WAS NOT THERE IN 4.5.0.
Please, JetBrains, do something about it in the existing 4.5 release - before going on to another all-improved release 5.0!