I've been doing a lot of debuggin' on a project lately to iron out the last few most irritating bugs out of one of the projects I'm working on.
This ofcourse involves a lot of small changes, rebuild, start, test, etc.
After 10 debug runs in a one hour period to test all the different cases my visual studio had reached 900Mb of memory usage and started throuwing Out-Of-Memory errors (Resharper didn't, it did that back in the 201 build) and finally collapsed. Disabling Resharper fixes the problem.
It's quite easy to reproduce on a reasonaly large solution (44MB binary+symbols when compiled). And during the whole process I have the Exceptions - Break on all exceptions truned on (maybe it has something to do with this issue, though I haven't tried).