Since I installed R#, there seems to be a small but nasty bug:
After every start of Visual Studio 2005, when I press F2 to rename something for the first time, R# asks me if I want to use the R# keyboard shortcut or the built-in one. This only happens with this one shortcut (AFAIK).
Perhaps it has something to do that I use Vista? (VS 2005 SP1 + Vista Update Beta).