The new version is getting steady and bugfree, but there are still several annoying problems in VS 2010:
First - there's an disturbing delay when using Ctrl + click for 'navigate to source'. I need to hold the Ctrl for about a second, before the selected word turns to link and register the click. In VS 2008 it reacts immediately.
Second - In WPF XAML editor there's still the problem with double auto-complete box appearance, probably native and ReSharper one. Somebody also noted it's happening in other editors too.
Also there should be a possibility to prevent autoformatting in XML comments in C# code OR set specific rules for XML comments formatting.
In XAML editor the settings for aligning attributes is not kept - still is used aligning to first attribute, not 'one indent' as is in settings.
Please fix at least these problems and you're ready to roll the RTM
And what's your notable problems in VS 2010?