I'm running the eval version of 3.02 at the moment and the VS IDE is extremely sluggish. I've disable my virus scanner (Kaspersky) as some people have suggested, and the solutions are on another physical hard-disk from Windows and Program Files. The solution is not very large, 50-100 source files, C#, not very complicated (IMHO). It's very quick to work with without R# and I've got a dual core 3.4 GHz machine running Vista.
As an example, pressing CTRL+TAB to move between two windows causes a delay of two seconds. Cutting/pasting lines in source, causes a similar delay.
Is it possible that I have configured something incorrectly?